The duo led Amakhosi to their highest league finish since the 2019/20 season, but that was not enough to keep them in a job.
There will certainly be no shortage of applicants for what remains one of the prime coaching roles on the continent, with a squad that has potential but has yet to fully realise it.
Chiefs may well look overseas for a new name, as they have with several recent appointments, but that comes with its own risks and challenges.
Here are five possible contenders for one of the hottest seats in South African football.
Pitso Mosimane
With three African Champions League titles and a wealth of experience not only on the continent but also in the Middle East, Mosimane would appear an obvious candidate for the role.
That is, of course, if Chiefs can afford him. Having been out of a job for some time, perhaps Mosimane would be open to negotiations.
He enjoyed success with SuperSport United and Mamelodi Sundowns domestically before heading to Al Ahly and then a host of clubs in the Middle East.
One of the sharpest football minds on the continent, it is unclear whether the Chiefs job appeals to him, having spoken in the past about a possible return to international football.
Benni McCarthy
The national team’s all-time leading scorer, the man who netted South Africa’s first goal at a FIFA World Cup, and a UEFA Champions League winner with FC Porto, the 47-year-old has also emerged as an impressive coach.
He cut his teeth with Cape Town City and AmaZulu, worked alongside Erik ten Hag at Manchester United, and is now gaining experience as national team coach of Kenya’s Harambee Stars.
McCarthy grew up a Chiefs fan and, although he ended his playing career at Orlando Pirates, would no doubt jump at the chance to lead his boyhood club.
That is, of course, unless the Bafana Bafana job becomes available after the 2026 World Cup.
Eric Tinkler
One of the best tactical coaches in the Betway Premiership, Tinkler is currently out of work after leaving Sekhukhune United before the end of last season.
He would be a pragmatic appointment, though perhaps not one to excite supporters. Having previously coached Pirates, he understands the demands that come with leading one of Soweto’s giants.
He is meticulous in his preparation, though there is a perception that he starts strongly at clubs before losing momentum over time.
Ernst Middendorp
They wouldn’t, would they? The man who came closest to delivering a league title to Chiefs in recent years could potentially be considered for a third spell in charge.
He knows the club, understands the league and works well with young players, though he does have a habit of rubbing people up the wrong way.
He arguably should have won the 2019/20 league title and may well have done so had COVID-19 not disrupted the season. Chiefs struggled to regain momentum in the Gauteng bio-bubble and lost the title on the final day after a 1-1 draw with lowly Baroka FC.
Rulani Mokwena
An outside bet if ever there was one, but football can be unpredictable. Some find Mokwena too intense, but there is no doubt he is ambitious and obsessed with operating at the highest level.
He is currently with Al-Ittihad in Libya on a substantial salary, which could prove a stumbling block for Chiefs. He has also previously coached Mouloudia Alger and Wydad Casablanca.
At Mamelodi Sundowns, Mokwena won four league titles, while he also had a brief spell in charge of Chiefs’ bitter rivals, Pirates. As the son of former Pirates player Julius Sono and nephew of Jomo Sono, his ties to that side of Soweto may ultimately run too deep for a move to Naturena.